Hecker Markus, Duncker Dirk J. (eds.) Cardiac Mechanobiology in Physiology and Disease

Springer, 2023. — 358 p. — (Cardiac and Vascular Biology 9). — ISBN 978-3-031-23964-9.This book presents the latest findings in the field of cardiac mechanobiology in health and disease.Cardiac mechanobiology provides knowledge of all aspects of mechanobiology of the heart. Cardiomyogenesis is discussed as well as the mechanobiology of cardiac remodeling and regeneration. The molecular mechanisms of mechanoperception and mechanotransduction in cardiomyocytes are explained, as well as stretch induced differentiation of cardiomyocytes derived from induced pluripotent stem cells.This volume of the series Cardiac and Vascular Biology complements the volume Vascular Mechanobiology in Physiology and Disease (volume 8) published in this series. The book is aimed at clinicians as well as researchers in cardiovascular biology, bioengineering and biophysics, and also represents an educational resource for young researchers and students in these fields.Cardiac Mechanoperceptio​n and Mechanotransduct​ion:​ Mechanisms of Stretch Sensing in Cardiomyocytes and Implications for Cardiomyopathy
Mechanotransduct​ion in Heart Development
Mechanobiology of Cardiac Growth in Health and Disease
The Role of Mechanosensitive​ Signaling Cascades in Repair and Fibrotic Remodeling of the Infarcted Heart
Mechanobiology of Cardiac Fibroblasts in Cardiac Remodeling
Mechanobiology of Cardiac Remodelling in Cardiomyopathy
Biophysical Stretch Induced Differentiation and Maturation of Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Mechanical Considerations of Myocardial Tissue and Cardiac Regeneration
Mechanobiology of Exercise-Induced Cardiac Remodeling in Health and Disease
Cardiac Microvascular Endothelial Cells and Pressure Overload-Induced Cardiac Fibrosis
Cellular and Subcellular Mechanisms of Ventricular Mechano-Arrhythmogenesis​
Computational Biomechanics of Ventricular Dyssynchrony and Resynchronizatio​n Therapy
Therapeutic Innovations for Heart Failure